Dolutegravir 50 mg Indication:

Naivex (Dolutegravir) is an FDA-approved medicine. Is used for the treatment and therapeutic approach of HIV infection. Naivex is an integrase inhibitor. By integrating blockade, HIV integrase inhibitors prevent their multiplication and can reduce the amount of HIV in the body.

Brand name:Naivex

Active Ingeridents:Dolutegravir 50 mg

Company Name:Hetero Labs Limited

Package:30 Tablets/Bottles

Strength :50mg

Dolutegravir 50 mg Mechanism of action:

Naivex (Dolutegravir) is an FDA-approved drug for the treatment of HIV infection. Dolutegravir is an integrase inhibitor. Mechanism of action:Naivex (Dolutegravir)is an HIV-1 antiviral agent. It inhibits HIV integrase by binding to the active site and blocking the strand transfer step to retroviral DNA integration. This is an essential step of the HIV replication cycle and will result in an inhibition of viral activity. Naivex (Dolutegravir)has a mean EC50 value of 0.5 nM (0.21 ng/mL) to 2.1 nM (0.85 ng/mL) in peripheral blood mononuclear cells (PBMCs) and MT-4 cells.Dosage and Administration:Use Naivex (Dolutegravir)as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Dolutegravir Dosage and Administration:

Use Naivex (Dolutegravir) as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • An extra patient leaflet is available with Naivex (Dolutegravir). Talk to your pharmacist if you have questions about this information.
  • Take Naivex (Dolutegravir ) by mouth with or without food.
  • Do not take an antacid or product that has magnesium, aluminum, iron, or calcium in it; sucralfate; or buffered medicines within 6 hours before or 2 hours after you take dolutegravir.
  • Take Naivex (Dolutegravir) on a regular schedule to get the most benefit from it. Taking Naivex (Dolutegravir) at the same time each day will help you remember to take it.
  • Continue to take Naivex (Dolutegravir) even if you feel well. Do not miss any doses.
  • If you miss a dose of dolutegravir, take it as soon as possible. If it is within 4 hours of your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
  • Ask your health care provider any questions you may have about how to use dolutegravir.

Dolutegravir WARNING:

Naivex is a prescription drug and should be used under proper medical guidance and advice. The information provided here is for general educational purposes only and does not constitute medical or pharmaceutical advice which should be sought from qualified medical and pharmaceutical advisers.

Dolutegravir Side effects:

The most common adverse reactions with Naivex were headache and fatigue and when used with RBV in decompensated cirrhosis were fatigue, hypersensitivity reactions, Effects on serum liver biochemistry in patients> Hepatitis B or C, Co-Infection, Fat Redistribution, Immune Reconstitution Syndrome, Sleep Problems, Fatigue.

Headache; tiredness; trouble sleeping.


Store Naivex (Dolutegravir) at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Keep Tivicay (Dolutegravir) out of the reach of children and away from pets.


Before taking Naivex (Dolutegravir), tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: liver disease (such as hepatitis B, hepatitis C), kidney disease.